Society has already seen multiple potential futures of neurotechnologies through the multifaceted lens of science fiction. We do not know which of those futures we will come to live, but the strong force in society's evolutionary process will likely continue to be the insight and oversight developed by the bioethics community, pushing and being pushed by the advances of technology, improvements in medical care, and market competitiveness.

Direct-to-consumer advertising of healthcare products refers to a variety of marketing practices based on a combination of information and promotion strategies directed at consumers through different media such as radio and television broadcasts, newspaper and magazine ads, and, more recently, through the Internet. The principal form of marketing used by the pharmaceutical industry is the distribution of free samples to physicians but DTCA is an increasing part of global promotional spending for prescription drugs. Latest estimates suggest that DTCA now represents (...) an annual $3.2 billion enterprise for the U.S. pharmaceutical industry. Findings from the literature show that these substantial efforts are geared toward the newer pharmaceuticals for chronic conditions with huge market potentials. The lion's share is going to the 20 most prescribed pharmaceuticals. (shrink)

A brain-computer interface technology that can decode the neural signals associated with attempted but unarticulated speech could offer a future efficient means of communication for people with severe motor impairments. Recent demonstrations have validated this approach. Here we assume that it will be possible in future to decode imagined (i.e., attempted but unarticulated) speech in people with severe motor impairments, and we consider the characteristics that could maximize the social utility of a BCI for communication. As a social interaction, communication (...) involves the needs and goals of both speaker and listener, particularly in contexts that have significant potential consequences. We explore three high-consequence legal situations in which neurally-decoded speech could have implications:Testimony, where decoded speech is used as evidence;Consent and Capacity, where it may be used as a means of agency and participation such as consent to medical treatment; andHarm, where such communications may be networked or may cause harm to others. We then illustrate how design choices might impact the social and legal acceptability of these technologies. (shrink)

Enfleshed: Ecologies of Entities and Beings brings together practitioners, thinkers, and artists from across Eurasia to collectively explore multispecies ecologies. The volume reflects anthrodecentric and embodied approaches to collaboration and knowledge production -- processes that are always interwoven with a multitude of entities and actors. In this book, the contributions flow like a river across the Eurasian continent, branching out into all directions. The contributors engage in an exploration of experimental epistemic alliances, which operate as a way to learn and (...) make new dialogic relations. The conflicts generated by ecological disaster, war, the global economy, identity politics, and the power structures of knowledge production and science here intertwine with shamanisms, rituals, magic, speculation, politics, and poetics. How do we imagine an active and implicated role of the human as one being among other beings? What might this entail, and what might this generate?"--Page 4 of cover. (shrink)

New agrifood technologies are often difficult to grasp for the public, which may lead to resistance or even rejection. Insight into which technology features determine public acceptability of the technology could offer guidelines for responsible technology development. This paper systematically assesses the relative importance of specific technology features for consumer response in the agrifood domain in two consecutive studies. Prominent technology features were selected from expert judgment and literature. The effects of these features on consumer evaluation were tested in a (...) consumer study. Fictitious technologies were used to avoid any uncontrollable contextual influences that existing new technologies may evoke. Results show that technologies that were seen as more natural and newer were perceived less risky, more beneficial, and were evaluated more positively. Technologies applied to food were judged to be more beneficial, but also more risky than those applied to non-food. Technologies used in the production process were perceived to be less risky and evaluated more positively than those used in the product. Technologies owned by the market leader were perceived to be more beneficial, and evaluated more positively than those that were freely available. In a next study, effects of the technology features on consumer response were tested for existing new agrifood technologies. This study replicated the results for perceived naturalness, perceived newness, and place in the production process where the technology is applied. However, in contrast to the first study, we did not find an effect of application area and technology ownership. (shrink)

Zoals bekend is de verhouding tussen filosofie en politiek problematisch. De veroordeling van Socrates door de polis maakte diepe indruk op zijn leerling Plato. Mede om dit soort misstappen te voorkomen ontwierp deze een ideale staat waarin filosofen koningen moesten worden. Vanuit dit idee probeerde hij ook Dionysus, de heerser van Syracus, tot een wijsgerig verantwoorde politiek te brengen. De mislukking van dit Siciliaans avontuur heeft velen na hem ervan overtuigd dat filosofen zich beter niet in kunnen laten met politieke (...) besluitvorming. Immers, Plato’s poging om Dionysus tot een wijsgerig verantwoorde politiek te brengen strandde jammerlijk. Maar, filosofen zijn natuurlijk hardleers en de aantrekkingskracht van het rijk der mensen en dingen op hen, die zich zo thuisvoelen in het rijk der ideeën valt niet altijd te loochenen. Hoewel voor Plato de politieke arena van alledag wezenlijk ongeschikt bleek te zijn voor filosofische uiteenzettingen, heeft toch zijn leerling en collega Aristoteles zich nog korte tijd met het onderwijs aan de jonge Alexander de Grote bemoeid – hoewel Aristoteles’ ambities al bescheidener waren dan van Plato. Het verhaal wil zelfs, dat Alexander op diens veldtochten een exemplaar van het werk van Homerus met aantekeningen van Aristoteles erin bij zich droeg. Na de dood van Alexander werd de anti-Macedonische atmosfeer in Athene voor Aristoteles zodanig bedreigend dat hij de stad verliet, om te voorkomen ‘dat de polis zich ten tweede male aan de filosofie bezondigde.’ Wie wel in het lot van Sokrates heeft moeten delen, is Thomas More, de auteur van het in 1516 verschenen ‘Utopia’. More weigerde Henry VIII als hoofd van de kerk te erkennen en moest dat met zijn dood bekopen. Dit vonnis vloeide dus niet direct voort uit het boek waarmee More zo bekend zou worden. Wellicht had More geleerd van de eerdere moeizame betrekkingen tussen filosofie en politiek en had hij daarom besloten om zich over ‘Ou-topia’ of ‘Nus-quama’ te buigen: over niet-plaats of nergens. Het in dialoogvorm opgetekende reisverhaal gaf op indirecte wijze kritiek op het Engeland van zijn tijd. Waarschijnlijk nog belangrijker dan het vermijden van risico’s door het schrijven over een niet reëel bestaande samenleving was het voordeel dat More op die manier een geheel ander beeld van een samenleving kon opstellen en beschrijven – ongehinderd door contingente omstandigheden, praktische bezwaren of politieke obstakels. More sloot de dialoog in ‘Utopia’ af met een korte overweging, waarin de auteur zegt zich nauwelijks te kunnen voorstellen dat deze samenleving ergens gerealiseerd zou kunnen worden. Vele lezers hebben deze overweging echter niet gezien of serieus genomen, zodat er al snel een ernstig meningsverschil over het genre van de utopie ontstond: vormde een utopie een blauwdruk voor een ideale samenleving die zonder meer ingevoerd zou moeten worden, of moest de utopie veeleer gelezen worden als een mengvorm van kritiek en ideaal – kritiek op de bestaande samenleving en richtinggevend ideaal voor nastrevenswaardige veranderingen van de huidige samenleving? (shrink)

Tim French, Wiebe van der Hoek, Petar Iliev and Barteld Kooi. Succinctness of Epistemic Languages. In: T. Walsh (editor). Proceedings of the Twenty-Second International Joint Conference on Artificial Intelligence (IJCAI-11), pp. 881-886, AAAI Press, Menlo Park.

One widespread argument against the efficacy of subjective well-being as a measure of well-being is the adaptation problem as formulated by Sen and Nussbaum: the phenomenon that people may adapt to deprivation and find satisfaction or happiness in objectively bad circumstances. It is not generally noticed that there are two distinct arguments for why the phenomenon of adaptation is a problem for subjective well-being as a measure of well-being. The Axiological Adaptation Argument is a counter-example to theories of well-being that (...) rely on mental states. The Epistemic Adaptation Argument illustrates that levels of happiness or satisfaction cannot be measured well when people have adapted. I argue that the most serious threat to subjective well-being measures is not the Axiological Argument, but the Epistemic Argument. I reflect on the implications the epistemic problem has for the empirical literature in general, and for research on the phenomenon of adaptation in particular. (shrink)

Results of two survey studies are presented. It is shown that attitudes of the public about "technology in general" are not stable and can easily be affected by how the subject is introduced. Eight areas of technology are compared on the basis of empirical relations in attitudinal judgments, in attribute ratings, in self- assigned importance weights of attributes, and in importance of reference groups and persons. On the basis of similarities in these four kinds of judgments, three clusters of technology (...) areas were identified: a cluster of modern reproductive technologies, an information cluster containing automation, computer, and communication technologies, and a cluster containing nuclear energy and military technology. The attitude toward "technology in general" can not be considered as an aggregation of attitudes toward these areas of technology: The relations between general attitude and specific attitudes are only moderate to negligible. (shrink)

Exploration of Alfred North Whitehead's influence on Maurice Merleau-Ponty's ontology of nature.

Legal and moral reasoning share much methodology, and they address similar problems. This volume charts two shared problems: the relation between theory, principles and particular judgments; and the role of facts and factual assertions in normative settings. The relation between 'theory' and 'practice' and between 'principle' and 'particular judgment' has become the subject of much debate in moral philosophy. In the ongoing debate, some moral philosophers refer to legal philosophy for a support of their views on the primacy of 'practice' (...) over 'theory'. According to them, legal philosophy should have a more balanced view in that relation. In the contributions to Part One this claim is critically analysed. The role of the facts is underestimated in discussions on legal reasoning and legal theory, as well as moral reasoning and ethical theory. Factual statements enter into moral and legal discussions not only because they link the conclusion with a rule. They also play a role as background assumptions in supporting a theory. Its focus on the role of facts in normative reasoning makes this book of special interest to scholars of legal and moral argumentation. (shrink)

In the present work we illustrate how two sorts of defeasible reasoning that are fundamental in the normative domain, that is, reasoning about exceptions and reasoning about violations, can be simulated via monotonic propositional theories based on a bimodal language with primitive operators representing knowledge and obligation. The proposed theoretical framework paves the way to using native theorem provers for multimodal logic, such as MleanCoP, in order to automate normative reasoning.

Many researchers studying subjective wellbeing (SWB) understand SWB as a concept that is close to Bentham’s notion of happiness. This conception of happiness is philosophically controversial, because it treats pleasure as a homogenous experience. I analyze an important deviation from Bentham in John Stuart Mill’s Utilitarianism and its relevance for SWB research: qualitative differences in pleasurable experiences. I argue that in cases where lives involving qualitatively different experiences are compared, Mill’s qualitative perspective is incompatible with an important assumption in the (...) SWB literature: that happiness can be meaningfully rated by people on a scale. I illustrate the problem by means of the question of whether becoming a parent makes people happier. I analyze whether the problem can be avoided on alternative views of happiness, but argue that on all plausible accounts of happiness, the problem persists. I conclude that the problem it poses for self-reported happiness is genuine and should be acknowledged by SWB researchers. I end by discussing the ways in which this conclusion can help the study of happiness move forward. (shrink)

Four experiments examined the strategies that individuals develop in sentential reasoning. They led to the discovery of five different strategies. According to the theory proposed in the paper, each of the strategies depends on component tactics, which all normal adults possess, and which are based on mental models. Reasoners vary their use of tactics in ways that have no deterministic account. This variation leads different individuals to assemble different strategies, which include the construction of incremental diagrams corresponding to mental models, (...) and the pursuit of the consequences of a single model step by step. Moreover, the difficulty of a problem (i.e., the number of mental models required by the premises) predisposes reasoners towards certain strategies. Likewise, the sentential connectives in the premises also bias reasoners towards certain strategies, e.g., conditional premises tend to elicit reasoning step by step whereas disjunctive premises tend to elicit incremental diagrams. (shrink)

This article presents the results of a qualitative study on the ethical aspects of inclusion practice for radiotherapy patients taking part in clinical research. The study focused on the standards and values of this process. Patients and physicians were interviewed about their views and experiences. Analysis of these interviews showed that candidate research participants need better protection from unwanted factors that could influence their choice about participation. Researchers need proper education about regulation, codes and directives in the field of research (...) ethics, and they should be aware of the underlying ethical concepts of these regulations. A sound institutional ethics policy is necessary in order to guide medical staff in decisions about the inclusion of patients in trials. (shrink)

The scientific advances made in the last two centuries have drastically improved the quality and structure of human existence. Exploring the history of that technological progress, and the numerous and complex elements that propelled its development, the _Encyclopedia of Technological Progress_ attempts to comprehensively classify the theories and hypotheses proposed in modern human history on the effects, meaning, and control of these advances. This massive and learned reference work draws on a wide range of disciplines in its study of technological (...) development, including philosophy, sociology, theology, history, and literature, as well as writings found in newspapers, political speeches, letters, and sermons, among other sources. “It is exceedingly important... that we should seek to understand more deeply the nature of technological development and very timely that this book should have appeared now to give distance and perspective to our efforts in this direction.”—Alexander King, president of the Club of Rome. (shrink)

In this paper we study AGM contraction and revision of rules using input/output logical theories. We replace propositional formulas in the AGM framework of theory change by pairs of propositional formulas, representing the rule based character of theories, and we replace the classical consequence operator Cn by an input/output logic. The results in this paper suggest that, in general, results from belief base dynamics can be transferred to rule base dynamics, but that a similar transfer of AGM theory change to (...) rule change is much more problematic. First, we generalise belief base contraction to rule base contraction, and show that two representation results of Hansson still hold for rule base contraction. Second, we show that the six so-called basic postulates of AGM contraction are consistent only for some input/output logics, but not for others. In particular, we show that the notorious recovery postulate can be satisfied only by basic output, but not by simple-minded output. Third, we show how AGM rule revision can be defined in terms of AGM rule contraction using the Levi identity. We highlight various topics for further research. (shrink)

Due to its extraordinary predictive power and the great generality of its mathematical structure, quantum theory is able, at least in principle, to describe all the microscopic and macroscopic properties of the physical world, from the subatomic to the cosmological level. Nevertheless, ever since the Copen hagen and Gottingen schools in 1927 gave it the definitive formu lation, now commonly known as the orthodox interpretation, the theory has suffered from very serious logical and epistemologi cal problems. These shortcomings were immediately (...) pointed out by some of the principal founders themselves of quantum theory, to wit, Planck, Einstein, Ehrenfest, Schrodinger, and de Broglie, and by the philosopher Karl Popper, who assumed a position of radical criticism with regard to the standard formulation of the theory. The aim of the participants in the workshop on Open Questions in Quantum Physics, which was held in Bari (Italy), in the Department of Physics of the University, during May 1983 and whose Proceedings are collected in the present volume, accord ingly was to discuss the formal, the physical and the epistemo logical difficulties of quantum theory in the light of recent crucial developments and to propose some possible resolutions of three basic conceptual dilemmas, which are posed respectively ~: (a) the physical developments of the Einstein-Podolsky-Rosen argument and Bell's theorem, i. e. (shrink)

ment on the same propositions, and is plagued by impossibility re- 2. What is the role of independence in judgment aggregation sults. In this paper we study the central notion of independence in..